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Monday, January 5, 2026

Nature Chemistry vs. Synthetic Science: Harnessing the Power of Both Worlds: Summary & Review of Article by Jiya lal verma


     This article explores the differences between nature chemistry and synthetic science and how they can be used to complement one another. The author notes that nature chemistry is “the study of chemical processes and compounds that occur naturally in the environment,” things like photosynthesis and human enzymic reactions in our bodies. As noted below, natural chemistry is often more complex than synthetic chemistry, at least it is now.




     Synthetic science involves human innovation and “designing and creating new materials, chemicals, and processes that do not exist in nature.” Below are some of its advantages.



     Nature chemistry is seen by many to be more environmentally benign than synthetic chemistry, but that is not always the case, and generalizations that something natural is better than something synthetic are often not true. This will become even more the case as synthetic science utilizes things like “green chemistry” and other sustainable approaches to materials and chemistry.

     The author points out that both natural and synthetic chemistry have enabled lifesaving and life-improving medicines. Synthetic-based medicine has resulted in better targeted therapies, vaccines, and personalized medicine. The complexity inherent in some natural processes has enabled many natural processes to be remarkably energy efficient, with that efficiency difficult or not yet possible to duplicate with synthetics. There is a fallacy among environmentalists and many people that natural is always better than synthetic, but this is simply not true.

     The author states that a collaboration of natural and synthetic methods can often provide the best results. Thus, finding synergies between the two methods is very important. The examples given include biomimicry, where natural designs are copied or imitated. There are many documented successes of biomimicry for solving problems. Another example is using natural medicinal products and subjecting them to synthetic alterations, which has resulted in more effective medicines. Green chemistry is mentioned again as an example:

Techniques like biocatalysis and the use of renewable feedstocks are reducing the environmental impact of chemical production.”

     Natural and synthetic chemistry are often combined in advanced materials, including bio-plastics:

“…bio-based plastics combine the durability of synthetic polymers with the biodegradability of natural materials.”

     More examples of natural/synthetic collaboration include artificial photosynthesis, bio-inspired robotics, and CRISPR technology.

CRISPR, a revolutionary gene-editing tool, combines natural bacterial defense mechanisms with synthetic biology. This technology has the potential to treat genetic disorders, improve crop yields, and even combat infectious diseases.”

     Challenges and future direction include ethical considerations. On this subject, I am firmly against applying the Precautionary Principle. While ethics must be considered, we also need to get things done and not ban processes that can be useful, even if they have some negative effects. Another hurdle that is noted is the difficulty of matching the complexity of natural chemistry. Here, the author notes that:

Advances in computational modeling and machine learning may help bridge this gap {in replicating natural systems}.

     The author calls for a balance of innovation and sustainability.

Nature chemistry and synthetic science are not rivals; they are partners in innovation. By harnessing the wisdom of nature and the creativity of synthetic science, we can address some of the most pressing challenges of our time. From developing sustainable materials to curing diseases and combating climate change, the synergy between these fields holds the key to a brighter future.”

As we continue to explore the best of both worlds, the possibilities are limitless. The collaboration between nature chemistry and synthetic science will shape the future of science, technology, and society, paving the way for a more sustainable and innovative world.”



References:

 

Nature Chemistry vs. Synthetic Science: Harnessing the Power of Both Worlds. Jiya lal verma. Super Chemistry Classes. Nature Chemistry vs. Synthetic Science: Harnessing the Power of Both Worlds - Super Chemistry Classes

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